What is strontium-89 used for?
Strontium chloride Sr 89 is used to help relieve the bone pain that may occur with certain kinds of cancer. The radioactive strontium is taken up in the bone cancer area and gives off radiation that helps provide relief of pain.
How does strontium-89 Treat cancer?
This medication is used to: Strontium-89 chloride is in a class of drugs known as radioisotopes. It delivers radiation to cancer sites and ultimately decreases bone pain. The length of treatment depends on the types of drugs you are taking, how well your body responds to them, and the type of cancer you have.
Is strontium-89 still available?
Radiopharmaceuticals should only be used by physicians who are qualified by training and experience in the safe use and handling of radionuclides.
How does strontium-89 reduce bone pain?
Radiopharmaceutical-induced pain flare Strontium-89, Rhenium-186 hydroxyethylidene diphosphonate, and Samarium-153 are systemically administered beta-emitting calcium analogues taken up by bone in areas of osteoblastic activity and which may help relieve pain caused by blastic bony metastases (McEwan 1997).
What are the side effects of taking strontium?
Strontium ranelate might cause side effects such as stomach pain, diarrhea, and headache in some people. This form of strontium is not available in the U.S. Taking very high doses of strontium by mouth is POSSIBLY UNSAFE. High doses of strontium might damage the bones.
What is strontium used for?
Strontium is best known for the brilliant reds its salts give to fireworks and flares. It is also used in producing ferrite magnets and refining zinc. Modern ‘glow-in-the-dark’ paints and plastics contain strontium aluminate. They absorb light during the day and release it slowly for hours afterwards.
Is strontium used in chemotherapy?
Abstract. Purpose: Strontium-89 (Sr-89) chloride is an effective palliative treatment of the bone metastases of prostate cancer. Chemotherapy has also been shown to have a palliative benefit in this disease.
How is SR-89 produced?
Strontium-89 has a half-life of 50.563 days and is produced via neutron capture by an enriched strontium-88 oxide target using the DOE’s High Flux Isotope Reactor, located at Oak Ridge National Laboratory. The product has a radionuclidic purity of >99.8% and is sold as strontium chloride solution in 0.1 N HCI.
How is strontium-90 USED?
Strontium-90 is used as a radioactive tracer in medical studies and in studies of agricultural crops. It is also used in beacons for navigating, remote weather stations and space vehicles. Strontium-90 is used in electron tubes to treat eye diseases and as a radiation source in industrial thickness gauges.
Who should not take strontium?
A specific prescription form of strontium, strontium-89, is LIKELY UNSAFE during pregnancy and breast-feeding. It is a radioactive material that might harm the fetus. It may also pass into breast milk and could harm a nursing infant. Heart disease: Don’t use strontium if you have high blood pressure or heart disease.
Is strontium supplement safe?
You do not know what amounts your body is getting when you take these supplements. You also do not know whether they can seriously harm you. Research from Europe suggests that patients on strontium ranelate may have an increased risk of heart attacks[1,3], blood clots,[1, 3] and serious skin reactions (DRESS syndrome).
Is strontium safe to take?
When taken by mouth: Strontium is LIKELY SAFE when taken in amounts found in food. The typical diet includes 0.5-1.5 mg of strontium per day. Taking a prescription form of strontium, known as strontium ranelate, for up to 10 years is POSSIBLY SAFE.