What is keratosis punctata palmaris et plantaris?
Keratosis punctata palmaris et plantaris (KPPP) is a simple punctuate palmoplantar keratoderma that displays autosomal dominant inheritance with variable penetrance. Lesions typically begin between early adolescence and age 30 years as 2- to 20-mm hyperkeratotic papules along the lateral margins of the digits.
What is acquired keratosis keratoderma palmaris et plantaris?
‘Keratoderma’ is a term that means marked thickening of the epidermis of the skin. ‘Palmoplantar’ refers to the skin on the soles of the feet and palms of the hands; these are the areas keratoderma affects most often. Palmoplantar keratoderma is also sometimes known as ‘keratosis palmaris et plantaris’.
Can keratoderma be cured?
Inherited palmoplantar keratodermas are not curable but symptoms can be controlled. The aim of treatment is to reduce the thickness of the skin and to soften the skin.
What is palmaris et plantaris?
Pustulosis palmaris et plantaris (PPP) is a rare and chronic inflammatory condition that primarily affects the palms of the hands and soles of the feet. Signs and symptoms of the condition generally develop during adulthood and include crops of pustules on one or both hands and/or feet that erupt repeatedly over time.
How is keratosis Punctata treated?
Treatment options include topical keratolytics, emollients and occasionally systemic retinoids for severe cases. Systemic retinoids, such as etretinate, carry the risk of associated side effects such as hepatotoxicity.
How do you treat hyperkeratosis of the feet?
There are several treatment methods for plantar hyperkeratosis, such as salicylic acid plaster and scalpel debridement, and conservative modalities, such as using a shoe insert and properly fitting shoes.
Is hyperkeratosis hereditary?
Epidermolytic hyperkeratosis is usually inherited in an autosomal dominant pattern. This means that one copy of a mutated gene is able to cause the disorder and can be inherited from either parent. If one parent is affected, each child has a 50% chance of inheriting the disease.
How do you get keratoderma?
Disease at a Glance These bumps can cause pain in some people. The condition is usually inherited in an autosomal dominant manner and can be caused by a genetic change in the AAGAB gene. Some people have used surgical approaches consisting of excision and skin grafting.
How is acquired Keratoderma treated?
If no such etiology is evident, then conservative treatment options include topical keratolytics (urea, salicylic acid, lactic acid), repeated physical debridement, topical retinoids, topical psoralen plus UVA, and topical corticosteroids.
What is plantar hyperkeratosis?
Plantar hyperkeratosis typically occurs when areas of the sole are put under too much pressure (for example, if ill-fitting shoes rub and pinch your feet). Excessive pressure triggers excessive keratin production, which results in the excessive thickening of the skin.
What causes keratosis Punctata?
Punctate palmoplantar keratoderma type I is a genetic disease, which means that it is caused by one or more genes not working correctly.
What is hyperkeratosis of the palms and soles?
Hyperkeratosis of palms and soles : clinical study Typical lesions of hyperkeratosis of palms and soles do not create any problem but when slight variation is there it becomes difficult to diagnose and that changes the line of treatment.
What is palmoplantar keratoderma (keratosis palmaris et plantaris)?
‘Keratoderma’ is a term that means marked thickening of the epidermis of the skin. ‘Palmoplantar’ refers to the skin on the soles of the feet and palms of the hands; these are the areas keratoderma affects most often. Palmoplantar keratoderma is also sometimes known as ‘ keratosis palmaris et plantaris’.
What are the signs and symptoms of hyperkeratosis?
A well-demarcated, thick, yellow hyperkeratosis is present over the palms and soles. An erythematous band is frequently present at the periphery of the keratosis. The surface is often uneven and verrucous. Painful fissures and hyperhidrosis are common.
Which physical findings are characteristic of hyperkeratosis of the wrists?
A well-demarcated, thick, yellow hyperkeratosis is present over the palms and soles. An erythematous band is frequently present at the periphery of the keratosis. The surface is often uneven and verrucous. Painful fissures and hyperhidrosis are common. Finally, it is usually nontransgredient, with a sharp demarcation of the lesions at the wrists.