What happens if you inject tinzaparin into a muscle?
Do not inject tinzaparin into a muscle. See section 3, “How to use tinzaparin”. This medicine may make you bleed more easily, so when you are being given other injections or having any procedures carried out, tell the doctor, nurse or dentist that you are using tinzaparin.
Where do you inject blood thinners when pregnant?
Although it can be intimidating, if your obstetrician or midwife prescribes Lovenox or anticoagulation therapy, it is because the risk of a clot outweighs the risk of the medication in your pregnancy. Lovenox is usually injected by the woman, twice daily under the skin of her abdomen.
What is tinzaparin used for in pregnancy?
Tinzaparin was given as a single daily prophylactic dose for women with a history of venous thromboembolism (VTE) or recurrent miscarriage and as a single daily therapeutic dose for women diagnosed with VTE.
Is tinzaparin safe in pregnancy?
Tinzaparin does not appear to cross the placenta. Tinzaparin is only recommended for use during pregnancy when benefit outweighs risk. One case each of cleft palate, optic nerve hypoplasia, and trisomy 21 syndrome have been reported in infants whose mothers received tinzaparin therapy during pregnancy.
Can you inject Clexane into stomach when pregnant?
Clexane is considered to be safe to use in pregnancy as it doesn’t cross the placenta so does not affect your baby.
How long does tinzaparin stay in your body?
Tinzaparin sodium has a bioavailability of around 90% following a subcutaneous injection. The absorption half-life is 200 minutes, peak plasma activity being observed after 4 to 6 hours. The elimination half-life is about 90 minutes.
Is Tinzaparin safe in pregnancy?
Can you inject heparin into stomach when pregnant?
For pregnant women and women who have given birth, heparin is the anticoagulant of choice and is recommended by the Royal College of Obstetricians and Gynaecologists. It does not cross the placenta, and therefore is considered to be safe.
Does Tinzaparin cross placenta?
How long does Tinzaparin stay in your system?
Where do you inject Clexane when heavily pregnant?
Clexane should be injected just under the skin. Remember: Do not inject yourself within 5 centimetres of your belly button or around existing scars or bruises. Change the place where you inject between the left and right sides of your stomach; depending on the area you were last injected.
Is tinzaparin safe to use during pregnancy?
Tinzaparin use in pregnancy: an international, retrospective study of the safety and efficacy profile These data provide reassuring maternal and fetal outcome information in pregnancies exposed to tinzaparin. These data provide reassuring maternal and fetal outcome information in pregnancies exposed to tinzaparin.
What is tinzaparin sodium used for?
Tinzaparin sodium is a low molecular weight heparin with antithrombotic properties. Tinzaparin sodium inhibits reactions that lead to the clotting of blood including the formation of fibrin clots, both in vitro and in vivo.
What is the molecular weight of tinzaparin sodium Xa?
The mean tinzaparin sodium anti-factor Xa activity is approximately 100 IU per milligram. The average molecular weight ranges between 5,500 and 7,500 daltons. The molecular weight distribution is: Tinzaparin sodium is a low molecular weight heparin with antithrombotic properties.
How much tinzaparin can you take in a day?
Maximum concentrations (Cmax) of 0.25 and 0.87 IU/mL are achieved following a single SC fixed dose of 4,500 IU (approximately 64.3 IU/kg) and weight-adjusted dose of 175 IU/kg of tinzaparin sodium, respectively.