What drugs are quinoline derivatives?
Quinoline Derivatives
| Drug | Drug Description |
|---|---|
| Dequalinium | A quaternary ammonium cation antimicrobial agent used to treat common infections of the mouth and throat that has been studied in the treatment of vaginal candidiasis. |
| Diiodohydroxyquinoline | Used in the treatment of amoebiasis. |
Which is an example of quinoline alkaloids?
Quinoline alkaloids such as quinine, quinidine, cinchonine, and cinchonidine (Fig. 4.8) were the first drugs developed to treat malaria and come from Cinchona officinalis and related Cinchona species (Rubiaceae) which naturally occur in Central and South America.
Which drug is based on quinoline structure?
The antimalarial drugs chloroquine, mefloquine, and amodiaquin are synthetic quinoline compounds, as are dibucaine hydrochloride, a long-acting local anesthetic that is commonly used as a topical agent to relieve pain from minor cuts and insect bites and stings, and cyanine, the oldest of an important class of dyes.
What is a quinoline in medicine?
The quinoline-containing antimalarial drugs, chloroquine, quinine and mefloquine, are a vital part of our chemotherapeutic armoury against malaria. These drugs are thought to act by interfering with the digestion of haemoglobin in the blood stages of the malaria life cycle.
Is there another name for quinine?
Quinine is available under the following different brand names: Qualaquin.
What makes up chloroquine?
Chloroquine is a medication primarily used to prevent and treat malaria in areas where malaria remains sensitive to its effects….Chloroquine.
| Clinical data | |
|---|---|
| IUPAC name (RS)-N’-(7-chloroquinolin-4-yl)-N,N-diethyl-pentane-1,4-diamine | |
| CAS Number | 54-05-7 |
| PubChem CID | 2719 |
| IUPHAR/BPS | 5535 |
Which of the following drug comes under the class of tropane alkaloids?
Plants that contain the tropane alkaloids atropine, scopolamine, and hyoscyamine include the following: Datura species (jimson weed, angel’s trumpet, thorn apple) Hyoscyamus niger (henbane) Atropa belladonna (deadly nightshade)
Is quinoline and quinine the same thing?
Quinine (1) is the most abundant cinchona alkaloid and it also belongs to the quinoline methanol family of quinoline antimalarials. It contains a basic aromatic heterocycle (the quinoline ring) and a side chain, which features a secondary alcohol, alkene, and cyclic amine (Fig.
Is there quinine in grapefruit?
The juice or grapefruit itself contains valuable and natural quinine, which is advantageous for the treatment of malaria. Quinine is an alkaloid with a long history of treating malaria, as well as lupus, arthritis and nocturnal leg cramps.