What is cyproterone acetate used for?
Cyproterone acetate is a potent steroidal antiandrogen with progestational activity. It is used alone or in combination with ethinyl estradiol or estradiol valerate in the treatment of women suffering from disorders associated with androgenization, eg, acne or hirsutism.
What happens when you take cyproterone acetate?
Cyproterone lowers levels of testosterone in the body and also blocks testosterone from reaching the cancer cells. It slows or stops the growth of prostate cancer.
Why is cyproterone acetate not available in the US?
Notably, although cyproterone has been used internationally for many years, it is not available in the US due to rare case reports of hepatotoxicity in men receiving high doses for prostate cancer (9).
What happens when you stop taking cyproterone acetate?
Cyproterone acetate can sometimes change the way the liver functions. If this happens, you will stop taking the drug, and your liver should return to normal. Tell your doctor if you notice any yellowish coloring on your skin or in your eyes.
When is the best time to take cyproterone?
Your dose will also be printed on the label of the pack to remind you about what the doctor said to you. Take your doses with a snack, or just after eating a meal. Swallow the tablets with a drink of water. Try to take cyproterone at the same times of day each day.
Does cyproterone cause weight gain?
Cyproterone acetate is an anti-androgen drug. Adverse effects that have been reported with its use include weight gain, depression, fatigue, breast symptoms and sexual dysfunction.
Can cyproterone cause weight gain?
Can you get cyproterone acetate in the US?
Cyproterone acetate is not available in the United States but has been used in other countries. The drug usually is administered daily in doses of 50 to 100 mg on days 5 through 15 of the treatment cycle.
What is cyproterone 50mg used for?
CYPROTERONE AN is also used to reduce abnormal sex drive in men. In women, androgens may increase hair growth, loss of scalp hair and secretion of oil from the sweat glands. By blocking these hormones, CYPROTERONE AN may slow or stop excessive hairiness, loss of scalp hair, acne, oily skin and dandruff.
Does cyproterone acetate stop hair loss?
Recent studies performed by Sinclair show that 200 mg/day spironolactone has an effect equal to 100 mg/day cyproterone acetate, determining in 44% of the cases reduced hair loss and hair regrowth. In 12% of the cases it stops the disease progression [24].
Can cyproterone cause blood clots?
Blood clots (or history of) or. Circulation disease (or history of) or. Stroke (or history of)—If these conditions already are already present, cyproterone may have a greater chance of causing blood clotting problems.
What are the ingredients in cyproterone acetate?
Each coated tablet contains cyproterone acetate 2 mg and ethinylestradiol 35 micrograms. Montanglycol wax. Cyproterone Acetate / Ethinylestradiol tablets are round, beige, coated tablets with no markings.
Does cyproterone acetate have an antiaggressive effect?
“A possible antiaggressive effect of cyproterone acetate”. Br J Psychiatry. 159 (2): 298–9. doi: 10.1192/bjp.159.2.298b. PMID 1837749. ^ Nomani H, Mohammadpour AH, Moallem SM, YazdanAbad MJ, Barreto GE, Sahebkar A (December 2019). “Anti-androgen drugs in the treatment of obsessive-compulsive disorder: a systematic review”.
How effective is cyproterone acetate for hirsutism?
The antiandrogen cyproterone acetate is highly effective in the treatment of acne and hirsutism. It also competitively inhibits intracellular androgen receptor function, but it has only 18.6% of the activity of spironolactone.
Can cyproterone acetate be combined with Im Te and Tu?
Cyproterone acetate (CPA) has been combined with im TE and oral TU. The anti-androgenic properties of CPA are effected by the blockade of T and DHT at the receptor level. There is also gonadotropin inhibition at the pituitary. The combination of two oral preparations in a true male pill was assessed with oral CPA and TU.