What is the best initial treatment for depression?
Choosing an antidepressant — For the initial treatment of severe depression, we use serotonin-norepinephrine reuptake inhibitors (SNRIs) or selective serotonin reuptake inhibitors (SSRIs).
Which antidepressant is best for anhedonia?
Studies show that medications including fluoxetine (Prozac®), escitalopram (Lexapro®) and ketamine (Ketalar®) can ease symptoms of anhedonia in patients with depression. Recent research has found that vortioxetine (Trintellix®) a newer medication, may have a significant impact on depression and social anhedonia.
What is the most effective treatment for depressed patients?
Medications and psychotherapy are effective for most people with depression. Your primary care doctor or psychiatrist can prescribe medications to relieve symptoms. However, many people with depression also benefit from seeing a psychiatrist, psychologist or other mental health professional.
Is clinical depression hereditary?
Causes. Depression is known to run in families, suggesting that genetic factors contribute to the risk of developing this disease. However, research into the genetics of depression is in its early stages, and very little is known for certain about the genetic basis of the disease.
What is the safest depression medication?
Among the newer antidepressants, bupropion and venlafaxine were associated with the highest case fatality rates. In addition, among SSRIs, citalopram and fluvoxamine appeared to be related to higher mortality rates in overdose, whereas fluoxetine and sertraline were the safest [188].
Is anhedonia caused by low dopamine?
Dopamine Deficiency: Dopamine is a signaling agent (or neurotransmitter) in the brain that plays a large role in our ability to experience pleasure. Thus a shortage of it can limit the ability to enjoy things and create the emotionally stunted feeling of anhedonia.
What is the main cause of clinical depression?
There’s no single cause of depression. It can occur for a variety of reasons and it has many different triggers. For some people, an upsetting or stressful life event, such as bereavement, divorce, illness, redundancy and job or money worries, can be the cause.